July 14, 2023 2:19 pm

systmeic enzymes

This blog post series explores enzymes’ role in healing, starting with systemic enzymes. In this post, we will focus on systemic enzymes.

Enzymes, support crucial chemical reactions that keep our systems running smoothly. However, as we age, our bodies produce fewer enzymes, making supplementation increasingly crucial for maintaining health.

Systemic enzymes have been staples in Eastern Medicine for centuries. Moreover, they are now making waves in Western practices. In fact, they rank just behind the microbiome in their importance for our well-being.

systemic enzymes

Systemic Enzymes

Systemic enzymes circulate throughout the body, unlike digestive enzymes that primarily function within the gastrointestinal tract. Once they enter the bloodstream, they impact various systems.

There are three primary systemic enzymes: lumbrokinase, serrapeptase, and nattokinase. Notably, lumbrokinase, particularly in its boluoke form, stands out as the most potent but also the most costly.

Conversely, nattokinase and serrapeptase, while less potent, are more affordable and are often combined with other enzymes.

Despite their lower potency—nattokinase being 1/36th and serrapeptase 1/294ths the strength of lumbrokinase—they frequently yield positive results in clinical tests with my clients.

systemic enzymes


Lumbrokinase, derived from earthworms, is a powerful systemic enzyme known for its ability to dissolve blood clots and thin the blood.

Specifically, Boluoke, a well-researched type of lumbrokinase, has undergone rigorous clinical trials in China and is celebrated for its safety and efficacy.

This enzyme is particularly effective in treating conditions such as atherosclerosis and hypertension. Moreover, it shows potential in reducing angina attack frequency and preventing strokes by improving aspirin’s effectiveness and lowering blood viscosity.

Furthermore, recent studies underscore its role in preventing post-surgical adhesions, especially after abdominal surgeries.

However, lumbrokinase may not be suitable for everyone due to specific contraindications. For instance, those on blood thinners like warfarin or aspirin should use Boluoke® only under medical supervision and discontinue it at least two weeks before any surgical procedure to avoid excessive bleeding.

Additionally, it is not recommended for pregnant or breastfeeding women, or individuals with bleeding disorders or a history of stroke, due to increased bleeding risks.

In my client base, lumbrokinase often shows positive results in autonomic response tests for various conditions, including viral infections and spike proteins.


Next, Serrapeptase, like Boluoke, is derived from silkworms and is extensively used in Japan and Europe for its anti-inflammatory properties.

It is highly regarded by researchers as the most effective enzyme for reducing inflammation.

Furthermore, Serrapeptase excels in pain relief by breaking down proteins that contribute to pain and swelling in conditions such as osteoarthritis and injuries.

Additionally, it aids in improving circulation by dissolving fibrin and enhances respiratory function by reducing mucus and inflammation in the airways.

In my client base, serrapeptase consistently delivers excellent results for clients suffering from pain and inflammation.

Systemic Enzymes


Finally, nattokinase, derived from fermented soybeans, is celebrated for its anti-inflammatory properties.

Not only does it reduce inflammation, but it also lowers blood pressure and minimizes blood clot risks by breaking down fibrin, thereby improving circulation and overall cardiovascular health.

Furthermore, it has shown potential in protecting brain health, as one study demonstrated its ability to reduce brain damage in rats.

In my client base, nattokinase has been incredibly effective for clients with high blood pressure, helping to normalize it while we tackle the underlying causes.


In conclusion, systemic enzymes are increasingly integral to my clients’ health protocols.

I determine the specific systemic enzyme each client needs using autonomic response testing.

For instance, Serrapeptase is often effective for managing inflammation and pain, whereas nattokinase and lumbrokinase are better suited for addressing blood clotting and cardiovascular issues.

Additionally, the ability of enzymes to dissolve scar tissue and internal thickening holds great promise.

As the understanding of systemic enzymes grows in Western medicine, their use is expected to become more prevalent.

Additional Reading