December 31, 2021 9:00 pm

Zeolite Binds Histamines

Several years ago,  I discovered zeolite’ potent ability to bind and neutralize histamines in the digestive tract.

This revelation transformed my approach to managing histamine reactions, not only for myself but also for my clients.

Beyond its efficacy against histamines, zeolite tackles heavy metals, viruses, mold toxins, radioactive materials, and fluoride.

In this blog post, I’ll explore how zeolite supports gut health and enhances overall wellness.


Zeolite, a natural clay-like substance, has a honeycomb-like structure that discriminatingly takes in selective ingredients into its pores.

Moreover, its structure functions like a sieve, capturing specific molecules while excluding others. Grinding the zeolite into a microfine substance enhances this exceptional binding capacity.

Historically, zeolite has been used extensively to detoxify various toxins. Today, it is employed in treating wastewater, nuclear waste, cultivated fields, and animal husbandry and is increasingly used as an oral supplement in humans.

Of the more than 80 natural zeolites, clinoptilolite is the type recognised for its health benefits.

Silica Ratio

The silica content is crucial for the functionality of different types of zeolites.

In particular, it determines the absorption capacity and the types of materials the zeolite can take in.

Additionally, the silica content affects whether the zeolite maintains its structural integrity and passes through the gut intact. This is important, as it ensures that heavy metals do not leach from the compound.

A silica/aluminium ratio above five is necessary to ensure its effectiveness.


Health Benefits


Firstly, zeolites are renowned for their ability to detoxify harmful toxins.

This is because they take into their structure toxins, such as heavy metals and chemicals, preventing bodily damage.

At the same time, zeolites release essential minerals like sodium, calcium, magnesium, and potassium in exchange for these toxins.

This exchange ensures that zeolites do not strip essential nutrients from the body but instead exchange them for toxins.

Diamine Oxidase

Secondly, the human body processes or deactivates histamines through diamine oxidase enzymes (DAO) found in the digestive tract, which deactivates histamines.

However, this process has its limitations, mainly when DAO production is low, or histamine levels are high.

Significantly, zeolite overcomes these limitations. For example, animal studies have shown that zeolite can optimize DAO production by protecting the intestinal barrier.

Additionally, research indicates that zeolite has a high affinity for histamine, binding up to 82% of histamines in the gut when consumed within 30 minutes of a meal.

Therefore, zeolite effectively binds histamine in the digestive tract, pulling it into its porous cavities and eliminating it via the stool, thus bypassing histamine regulatory systems such as DAO, HNMT, and MAO.

That is, it specifically targets histamine in the gut, not affecting histamine generated elsewhere in the body.


Thirdly, ammonia, a waste product produced from excessive protein fermentation, increases ammonia production.

As a result, high ammonia levels can lead to liver and kidney issues and have been linked to conditions like irritable bowel syndrome and ulcerative colitis.

Consequently, zeolite has been found effective in binding to ammonia, offering potential benefits in managing these conditions.

Gut Microbiota

Next, pathogenic bacteria significantly contribute to histamine intolerance.

Specifically, a 2013 animal study demonstrated that zeolite not only improves gut integrity but also reduces pathogenic bacteria, including histamine-producing bacteria.

Additionally, Zeolite inhibits helicobacter (h. pylori), a common gut infection, by binding to excess ammonia, thus creating an environment were h. pylori cannot thrive.

Intestinal Barrier

Then, a substantial human study concluded that zeolite strengthens the intestinal barrier, showing a 30% improvement in zonulin, a marker of intestinal integrity, without affecting the status of critical nutrients.

Meanwhile, a 2017 animal study found significant improvements in the gut mucosa.

Additionally, a 2022 study indicated that zeolite heals intestinal damage. By coating the mucosal barrier, zeolite protects and repairs intestinal wall integrity.

Gut Brain Axis

Next, zeolite might indirectly affect the gut-brain axis through the central nervous system.

That is, research indicates potential benefits such as stress reduction and improved sleep from taking zeolite.

To clarify, although zeolites do not cross the intestinal barrier, let alone the blood-brain barrier, an indirect mechanism, such as the vagus nerve, is at play.

Furthermore, a 2013 animal study showed that zeolite counteracted oxidative stress and plaque accumulation in the brain, hypothesised to be due to its ability to maintain gut electrolyte balance.

This topic is currently an area of active research.



Then, zeolite has anti-inflammatory effects on the intestines. Specifically, it works by interacting with M Cells, which help the immune system by capturing harmful bacteria and presenting them to immune cells for destruction.

In other words, M Cells act like messengers, helping the body recognize and fight potential threats.

Additionally, research shows that zeolite increases the production of B-lymphocytes and IgA, which are crucial for the intestines’ defense against harmful bacteria.

Notably, IgA is particularly important because it controls inflammation and regulates the immune response, thereby helping the body adapt to bacterial challenges in the gut.


Next, the body’s redox system relies on enzymes to balance antioxidants and harmful molecules.

That is, excess reactive oxygen species cause cell damage and are linked to various diseases.

For instance, animal studies have consistently shown that zeolite acts as an antioxidant, activating enzymes to increase glutathione levels.

Thus, researchers hypothesise that zeolite’s antioxidant effects might stem from its ability to detoxify by binding to toxins in the intestine, thereby reducing the overall toxin load in the body.

Medical Use

Finally, using zeolite alongside regular medical treatments is gaining popularity.

For example, although zeolite is not a direct cancer treatment, it can support other treatments.

Consequently, in laboratory tests, zeolite has demonstrated the ability to slow or shrink tumour growth and even induce the death of cancer cells. It also appears to help limit the spread of cancer.

Additionally, strong anecdotal evidence suggests that zeolite can reduce side effects associated with cancer drugs and enhance treatment effectiveness.

In conclusion, research on interactions between zeolite and drugs has generally shown that zeolite does not impair the effectiveness of medications.

Common Misconceptions


Zeolite contains heavy metals

If you have ever been told this

You probably weren’t told…
Zeolite absorbs heavy metals and excretes them intact

The real issue is often fixable with the right knowledge.

I’ve helped hundreds if not thousands of people restore their health

Zeolite Heavy Metals Binder

Zeolite and Heavy Metals

Several years ago, a leading Australian building biologist observed that natural zeolite contains lead due to a Prop 65 warning in California.

Unfortunately, this observation has fuelled a widespread myth that zeolite leaches heavy metals into the human body, making it unsafe for consumption.

Such statements are misguided. Studies consistently show no leaching of heavy metals from zeolite.

For instance, a 2011 animal study demonstrated that zeolite reduced lead accumulation in the intestines by more than 70%, with a protective effect on brain tissue.

Thus, in Australia, some zeolite products are classified as ‘medical devices,’ safe for human use because they pass through the digestive tract intact.

Moreover, I have personally used zeolite for over a decade with my clients and myself, finding that it does not increase heavy metal levels but rather effectively removes them.


Nanoparticle zeolite is a binder

If you have been told this

You probably weren’t told…
Nanoparticle zeolite is a chelator, not a binder

The real issue is often fixable with the right knowledge.

I’ve helped hundreds if not thousands of people restore their health

Liquid Nanoparticle Zeolites

People frequently ask me for my view on liquid nanoparticle zeolite solutions.

Initially, it’s important to clarify that these are not binders but chelators.

While binders remain in the gut, these liquid nanoparticle zeolite solutions penetrate beyond the gut, being taken in inside cells to chelate toxins and draw them into circulation.

Consequently, when these solutions are used, a binder must still be used in the gut to capture the toxins.

Furthermore, the choice of zeolite is crucial. Some are synthetic rather than natural. In addition, the silica/aluminium ratio must remain above five for heavy metals to be bound.


Zeolite binds to minerals

If you have ever been told this

You probably weren’t told…
Zeolite binds preferentially to heavy metals

The real issue is often fixable with the right knowledge.

I’ve helped hundreds if not thousands of people restore their health

Binders Mercury Amalgams

Zeolite and Mineral Binding

Another common concern involves the ability of binders, including zeolite, to bind vital minerals inadvertently.

Some binders lack selectivity, indiscriminately binding to various things.

Others prioritise certain things over others, while some intelligently target only toxic things.

Zeolites, in particular, selectively adsorb specific molecules, allowing others to pass freely.

Research indicates that zeolites effectively adsorb heavy metals, yet essential minerals such as calcium, magnesium, and potassium are unaffected or minimally affected.

Additionally, studies suggest that zeolites function as ion-exchange materials, releasing certain essential minerals while taking in other things.


In conclusion, zeolite stands out as a versatile tool for health restoration.

Significantly, zeolite improves the integrity of the intestinal barrier.

Furthermore, it enriches the intestinal microbiome and enhances immune function by activating antioxidants.

Thus, Zeolite offers a brilliantly simple solution to managing histamine issues.

As a result, zeolite is increasingly included in my clients’ treatments due to its efficacy in detoxifying histamines and toxins.

To learn more about binders that help with histamine intolerance, check out my blog post, All About Binders And How To Use Them.

Follow me on Instagram and Facebook to continue the conversation.

Additional References

Published (2020 -





2013 - 2014

2011- 2012

2005 - 2010

Pre 2005